UB Care
Additional Warranty can be added to this product for other 12 or 24 months.
Discover more about our warranty policy.
Animal
Mouse, Rat
Dynamic Plantar Aesthesiometer - For Mechanical Stimulation
Product Code:37550
Category: Pain and Inflammation
Automates the assessment of “touch sensitivity” on the plantar surface of rats or mice. For assessment of hypersensitivity and allodynia for analgesia, nociceptive, neuropathic and postsurgical studies.
Unique automation features save significant time for the researcher.
Background
- The automated Dynamic Plantar Aesthesiometer (DPA) is a quick, accurate way of delivering mechanical stimulation and measuring a response.
- Impaired cutaneous sensation is usually first manifested in a loss of light touch detection. Mechanical stimulation is used clinically to diagnose pathologies of hyper- or hypo-aesthesia, brought about by drugs, neural pathology or experimental lesions.
Application & Disease Models
- Automatically detects and records latency time, and actual force at the time of paw withdrawal reflex.
- A movable force actuator is positioned below the plantar surface of the animal. The desired force and force speed (ramp) is applied, as pre-set by the operator.
- Increasing force is exerted by rigid Von Frey filament (0.5mm tip) until the animal twitches its paw.
- Adjustable touching force and touching pause (to control the stimulus approaching phase).
- Paw withdrawal detection is automatic. Manual detection is also available (useful if animal motor response is unusual).
- The device comprises:
- A movable touch-stimulator unit complete with filament actuator and adjustable angled-mirror
- A microprocessor controlled electronic unit with touch screen, graphic display, internal memory for data storage, USB key and optional printer
- Large testing surface (perforated metal platform), laser cut for smooth and precise grid spacing
- Modular animal enclosure offering from 3 to 12 spaces is convenient for holding rats and mice
- Supplied with accessories to work with both mice and rats.
- Data can be transferred to a computer via the memory stick.
- TTL outputs for Start/Stop and Detection (Manual/Automatic) as well as TTL Input for external start provide easy interface to external instruments such as DAQs. Analog output is also available.
Impaired cutaneous sensation is usually first manifested in a loss of light touch detection. So “mechanical” stimulation has a long history of effective clinical use to diagnose pa-thologies of hyper- or hypo-aesthesia, brought about by drugs, neural pathology or experimental lesions, etc.
The Dynamic Plantar Aesthesiometer was developed to apply a reproducible light touch to the rodent plantar surface, and quantify the force which causes the animal to react by withdrawing the paw.
| Feature | Benefit |
|---|---|
| The force is automatically applied | Consistency in force application, rate and direction |
| Maximum force is 100g | Works on a broader range of animal models, molecules, diseases |
| The user only has to press a button | The test is quicker and less tedious than VF hairs |
| Double click of the button triggers manual score | Possibility to use manual scoring when animal behaviour is difficult to automatically detect |
| Force threshold and ramp can be adjusted | More parameters to fit with virtually any experimental need |
| Touch force and touch pause can be adjusted | The way the probe approaches the paw can be changed, depending on paw sensitivity |
| Force automated or manual | The force threshold can be scored manually or automatically |
| General | |
|---|---|
| Read out and commands |
4,3 inches touch-screen (Resistive) |
| Power Requirements | Universal input 100-240 VAC, 50-60 Hz, 30W |
| Sound Level | Negligible |
| Operating Temperature |
10°C to 40°C; 5% to 95% RH (non-condensing) |
|
Operation | |
| Force Range |
0.1 to 100 grams, in 0.1g steps |
| Force Increasing Rate (ramp) | Adjustable in the interval 0 to 50 seconds, in 1 s steps |
| Latency Time | Display in 0.1s steps |
|
Measurement Mode |
Automatic |
|
Start Experiment |
By Start button, push buttons or TTL input |
| Stop experiment |
By Stop button, push buttons, cut-off or TTL input |
| Data input | Experiment protocol |
|
Data export |
.csv format |
| TTL/IO | Start/Stop, Detection Mode, Force level |
| Calibration | Calibration Weights (5g, 50g, 100g) |
|
Physical | |
| Total Weight | 10Kg |
| Shipping Weight | 13Kg |
| Dimensions (all parts) | 135 (w) x 40 (d) x 50 (h) cm (required space on table; all parts) |
| Packing Dimensions | 98x49x47 cm |
|
Warranty | |
| Warranty | Dynamic Plantar Aesthesiometer is covered by a 12-month warranty + 12 after product registration. |
| UB-Care | Additional UB-Care can be added for other 12 or 24 months |
Impaired cutaneous sensation is usually first manifested in a loss of light touch detection.
So “mechanical” stimulation has a long history of effective clinical use to diagnose pathologies of hyper- or hypo-aesthesia, brought by drugs, neural pathology or experimental lesions, etc.
The Dynamic Plantar Aesthesiometer was developed to apply a reproducible light touch to the rodent plantar surface and quantify the force which causes the animal to react by withdrawing the paw.
| 37550 Dynamic Plantar Aesthesiometer | |
|---|---|
| 37550-001 | Microprocessor controlled electronic unit |
| 37550-002 | Touch Stimulator, complete with probe actuator and adjustable angled-mirror |
| 37000-003 | Large Platform |
| 37400-327 | Supporting column (4) |
| 37000-007 | Modular Animal Enclosure |
| 37450-005 | Large Framed Perforated Metal Sheet |
| 37450-321 |
Plastic Case lodging, 2 Filaments (with umbrella), 2 Calibration Weights, 1 hex. Wrench 1.25 |
| E-AU 101 | Memory Key, including the user manual and Xpad software |
| Optional | |
| 37450-278 | Additional Stimulation Base, complete with perforated metal sheet and animal enclosure |
| 37100 | Set of 2 Durham Holders for Orofacial Stimulation |